YY1 and acute leukemia: With the confirmation of YY1 and lncRNAs as tumor regulatory networks, more and more researchers have conducted further studies on their crosstalk mechanism and found that YY1-regulated lncRNAs are involved in the regulation of esophageal squamous cell carcinoma, laryngeal squamous cell carcinoma, nasopharyngeal carcinoma, cholangiocarcinoma, gastric cancer, bladder cancer, melanoma, prostate cancer, acute leukemia and osteosarcoma.