Cell experiments revealed that HOTAIR promoted tumor growth and metastasis of tumor cells and inhibited apoptosis by miR-1/miR-206-YY1 axis.[71] GACAT1 binds to miR-422a to regulate the expression of YY1 mRNA and protein in NSCLC cells.[72] Finally, the research found that LINC00958 is associated with poor prognosis of breast cancer. The gene discussed is YY1; the disease is breast carcinoma.