SIRPA and colorectal carcinoma: CD47, the ligand of SIRPα, was shown to be elevated in CRC tumors by RNA-Seq data from the colon adenocarcinoma (COAD) cohort of The Cancer Genome Atlas (TCGA) database (Supplemental Figure 1A; supplemental material available online with this article; https://doi.org/10.1172/JCI162870DS1).