SIRT3 and pemphigus foliaceus: In this work, we confirmed a significant increase in the expression levels of AMPK, PGC-1α, and SIRT3 in miR-33–deficient macrophages; their downstream effects might be responsible for the resolution of PF via an increase in autophagy, decrease in apoptosis, amelioration of the inflammation, and improvement of mitochondrial homeostasis.