CHI3L1 and idiopathic pulmonary fibrosis: Our analysis revealed that miR-33 inhibition attenuated multiple genes from the IPF macrophage’s signature list, including CHI3L1, CHIT1, MERTK, CTSK, ITGB5, FN1 (fibronectin 1), LGMN (legumain), LPL (lipoprotein lipase), FABP5 (Fatty acid binding protein 5), LIPA (lipase A), and CTSZ (cathepsin Z) (Figure 8H and Supplemental Table 5).