After integrating our data set with the published data set, we first recognized the same clusters of CD4+ T cells, and secondly, when we compared the Trm score across healthy, NAFLD, and NASH conditions we confirmed that CD4+ T cells with Th1 and Th17 polarization states isolated from NASH patients had the lowest score (Supplemental Figure 4, A–D). This evidence concerns the gene CD4 and metabolic dysfunction-associated steatohepatitis.