PI3K/Akt/mTOR pathway is a critical carcinogenic pathway involved in tumorigenesis and progression in a wide variety of tumours, including PCa,14 non‐small cell lung cancer,30 breast cancer,31 lung cancer32 and colorectal cancer33 Previous studies have revealed that this pathway is associated with various cellular functions in PCa, such as cell proliferation, migration, invasion, apoptosis and autophagy.15, 34. Here, MTOR is linked to posterior cortical atrophy.