PI3K/Akt/mTOR pathway is a critical carcinogenic pathway involved in tumorigenesis and progression in a wide variety of tumours, including PCa,14 non‐small cell lung cancer,30 breast cancer,31 lung cancer32 and colorectal cancer33 Previous studies have revealed that this pathway is associated with various cellular functions in PCa, such as cell proliferation, migration, invasion, apoptosis and autophagy.15, 34. This evidence concerns the gene AKT1 and breast cancer.