Other conditions related with type 2 diabetes such as obesity have been associated with an increased risk of infections due to the role of adipose tissue in the production of proinflammatory cytokines (tumor necrosis factor (TNF)-α, interleukin (IL) 6, IL-1β, IL-18, monocyte chemoattractant protein (MCP)-1), proinflammatory adipokines, and other inflammatory products [24, 25]. The gene discussed is IL1B; the disease is obesity due to melanocortin 4 receptor deficiency.