Subanalyses in Asian patients by renal function were available from the RE-LY (Randomized Evaluation of Long Term Anticoagulant Therapy) trial12 and the J-ROCKET AF (Japan-Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation) trial13 (Table 2). This evidence concerns the gene F10 and Stroke.