Noticeably, depletion of Cxcr1/2 receptors impeded the oncogenic effects of GROα, preventing intraperitoneal dissemination of ovarian tumors and highlighted the possibility of targeting the miR-141/YAP1/GROα/CXCR1/2 signaling cascade to combat OvCa metastases. The gene discussed is CXCL1; the disease is ovarian neoplasm.