For example, pre-infusion and post-infusion cross-sectional thoracic contrast computed tomography scans in two patients with SS (each with MAGE-A4 H-scores >200, large baseline tumor burdens and treated with high afami-cel doses) confirmed the in vivo potency and anti-tumor activity of afami-cel (Patients A and B; Extended Data Fig. 4 and Supplementary Table 5). The gene discussed is MAGEA4; the disease is neoplasm.