Protein O-fucosyltransferase 1 (POFUT1) is highly expressed in GC, and its expression is positively correlated with aggressive tumor phenotypes, such as higher T and N classification as well as poor differentiation, indicating POFUT1 may facilitates its development as a biomarker for prognosis of GC [12]. This evidence concerns the gene POFUT1 and neoplasm.