In silico analysis of the published datasets from The Cancer Genome Atlas (TCGA) (https://portal.gdc.cancer.gov/) and GTEx V8 version (https://gtexportal.org/home/datasets) including 620 CRC tissues (tumor) and 789 normal colorectal tissues (normal) revealed a significant increase of SRSF2 mRNA expression in CRC tissues compared with normal colorectal tissues (p < 0.001; Fig. 1B). This evidence concerns the gene SRSF2 and colorectal carcinoma.