The biallelic compromise of one of 22 FANC genes involving the FA/BRCA repair pathway caused Fanconi anemia (FA) with an incidence rate of 1 in 300,000 live births and a prevalence rate of 1–9 per million [28, 29], which was reported to be the most frequent inherited cause of bone marrow disorder (BMF) clinically characterized by congenital malformations [29, 30]. The gene discussed is FANCA; the disease is bone marrow disorder.