The most strongly induced significant protein was interferon-induced protein with tetratricopeptide repeats (IFIT) 5 (fold change = 7.65, P = 0.021) (Fig S4A and D), consistent with previous reports of a type I interferon signature in neutrophils from COVID-19 patients (47, 56, 57, 58). Here, IFIT5 is linked to COVID-19.