TGFB1 and cancer: Further, six immune subtypes, including G1 (wound Healing), G2 (IFN-γ dominant), G3 (inflammatory), G4 (lymphocyte Depleted), G5 (immunologically quiet), and G6 (TGF-β dominant) in cancer proposed by Thorsson et al. (2018), were used to characterize intratumoral immune states and identify modules of immune signature (Thorsson et al., 2018).