LGALS9 and B-cell non-Hodgkin lymphoma: We observed that Gal-9 was upregulated in EBV+LCL and B-cell lymphoma cell lines, and we further confirmed that forced EBNA1 expression upregulated Gal-9 expression in 293T cells, whereas knockdown of EBNA1 expression downregulated Gal-9 expression in LCL cells.