GSTM1 and Increased total leukocyte count: In addition, univariate analysis of TFS showed that older age (>70 years, HR = 2.52, 95% CI 1.160–5.501, p = 0.012), presence of anemia (Hb <12 g/dL, HR = 2.92, 95% CI 1.248–12.233, p = 0.019), prior thrombosis history (HR = 4.25, 95% CI 2.506–24.785, p = 0.015), leukocytosis (>10 × 109/L, HR = 1.82, 95% CI 1.105–3.568, p = 0.041), and high LDH levels (HR = 1.68, 95% CI 1.114–2.425, p = 0.025) were associated with worse TFS in the present cohort.