As expected, the essential proteins JAK2/STAT3/STAT5/p‐STAT5/PI3K P85/AKT/p‐AKT/GSK3b decreased after DPYSL2‐KD in AML cells, while the expression of PI3K P110 did not change (Figure 5F). Here, DPYSL2 is linked to acute myeloid leukemia.