As expected, the essential proteins JAK2/STAT3/STAT5/p‐STAT5/PI3K P85/AKT/p‐AKT/GSK3b decreased after DPYSL2‐KD in AML cells, while the expression of PI3K P110 did not change (Figure 5F). This evidence concerns the gene JAK2 and acute myeloid leukemia.