Associated cardiovascular diseases include diabetes (PDLIM5, HDAC4, and TLE1) (31, 35, 37), cardiac development (PDLIM5) and myocardial aging (CASP12), hypertension (PFKP and TAB2) (31–33, 36), and intracerebral and intraventricular bleeding (RUNX1) and stroke (AXIN2) (24, 27). This evidence concerns the gene RUNX1 and stroke disorder.