identified a 10-gene signature based on probable predictive m6a regulatory genes, and these genes (METTL3, WTAP, RBM15, RBM15B, YTHDC2, YTHDF2, HNRNPC, FMR1, LRPPRC, and RBMX) were found to be negatively associated with STAD clinical stage. The gene discussed is METTL3; the disease is gastric adenocarcinoma.