To further explore the expression of Mena in OSCC, we analyzed RNA‐seq data of 399 TCGA patients with OSCC (tumor 369, normal 30) which was then used to identify differentially expressed genes (DEGs) and found that Mena was higher in tumor tissues (Average 7.232 in normal vs. 14.311 in tumor; P<0.0001) (Figure 1E). This evidence concerns the gene ENAH and neoplasm.