CXCL8 and COVID-19: However, we further enrolled IL-6 and IL-8 in regression analysis and found out that neither IL-6 nor IL-8 was statistically significant in multivariate regression analysis, which suggests that IL-6 and IL-8 weren't effective indicators for viral shedding duration in patients with non-severe COVID-19, and can't reach to the better sensitivity and specificity as compared to the level of nucleic acid.