SOD1 and amyotrophic lateral sclerosis: Based on these previously published papers, we evaluated longitudinally a group of SOD1-G93A ALS mice treated with RSV vs. a group of untreated animals with two goals in mind: (1) to assess the effects of RSV treatment on disease progression and overall survival; and (2) to compare the effectiveness of several biomarkers [i.e., CMAP amplitude, paw grip endurance (PGE), motor score (MS), and surface EIM] to detect disease onset and progression, as well as the potential drug efficacy of RSV in this model.