MAPK3 and epilepsy: The expression levels of FYN protein and phosphorylated extracellular signal-regulated kinase ERK1/2 (p-ERK1/2) were significantly increased in epilepsy models, and the expression of p-ERK1/2 was significantly decreased when FYN expression was downregulated, suggesting that the activation of the ERK1/2 signaling pathway may be regulated by Fyn expression (44).