In contrast, four target genes were presented with inverse expression in DLBCL, including MYD88, toll like receptor 4 (TLR4), TNF superfamily member 14 (TNFSF14) and the tripartite motif containing 25 (TRIM25) (Figures 9(v)–9(y)). Here, TLR4 is linked to diffuse large B-cell lymphoma.