ALKBH5 and Decreased total leukocyte count: In addition, ALKBH5 rs9913266 A allele demonstrated a significant relationship with the increased occurrence of DILI (P = 0.046), as well as the decreased occurrence of sputum smear-positive (P = 0.049), and rs4925144 TT genotype seemed to be a protective factor for leukopenia in PTB patients (P = 0.019).