CLEC7A and Peripheral demyelination: In conclusion, this study showed that LNT significantly improved central demyelinating disease by regulating dectin-1, promoting the conversion of microglial cells from the M1 status to the M2 status, enhancing anti-inflammatory and regeneration, inhibiting the occurrence of neuroinflammation, improving motor function and remyelination, and providing a novel potential candidate medicine for the remyelination stage in the treatment of central demyelination-associated diseases.