In multivariate logistic regression analysis, we found that preoperative TyG (OR = 8.207, 95% CI = 1.903-35.394, p=0.005), HSI (OR = 0.861, 95% CI = 0.765-0.969, p=0.013) and circulating Prdx1 (OR = 0.887, 95% CI = 0.816-0.963, p=0.004) were independently associated with NAFLD remission at three months after LSG (Table 4). This evidence concerns the gene PRDX1 and metabolic dysfunction-associated steatotic liver disease.