The deletion of the KIF20A remarkably alters cellular phenotypes, inhibits cell migration and invasion by reducing MMP-7 expression, as well as preventing cell proliferation by inactivating JNK signals, implying that KIF20A might function as a potential oncogene and a promising treatment target for NSCLC (Xie et al., 2020). Here, MAPK8 is linked to non-small cell lung carcinoma.