According to the results of WB presented in Figures 9(a) and 9(b), Cyt-c and caspase-3 expression in the islet tissue of rats was significantly higher in the T2DM group than in the NC group, whereas the Bcl-2/Bax ratio was significantly decreased, indicating that apoptosis of islet cells was significantly increased in rats in the T2DM group. This evidence concerns the gene CASP3 and type 2 diabetes mellitus.