However, new sequence variants were observed near this region in the exon 3 of LEP. Analysis of rs28954114 (+328G/A) in the 3′-UTR of LEP revealed that the mutant allele A was observed in one subject with obesity (P076) and two control subjects (C145 and C248) in heterozygous condition (Figures 3(a)–3(f)). This evidence concerns the gene LEP and Obesity.