Studies increasingly show that the aberrant expression of TRPV4 in tumor tissues is associated with cancer progression (Nilius et al., 2007; Prevarskaya et al., 2007; Fiorio Pla et al., 2012; Xie et al., 2017; Zhang et al., 2018; Liu et al., 2021). The gene discussed is TRPV4; the disease is neoplasm.