Amongst its actions, we have shown that apigenin is able to upregulate CD26 at the surface of human colorectal carcinoma (CRC) cells, including those of the HT-29, HRT-18 and Caco-2 cultured cell lines (Lefort and Blay 2011; Lefort et al., 2020). The gene discussed is DPP4; the disease is colorectal carcinoma.