SERPINE1 and Hyperglycemia: 5) AGIs may improve postprandial hyperglycemia, decrease oxidative stress, reduce systemic inflammation, lower plasminogen activator inhibitor-1 and fibrinogen levels, and attenuate coagulation activation (Hanefeld et al., 2004; Standl et al., 2014), which may mitigate the risk of cirrhotic decompensation.