SETD2 and neoplasm: To further investigate the relationship between KIRP tumor immunity, we performed the correlation analysis between KIRP immune checkpoint genes (CTLA4, HAVCR2, PDCD1, PDCD1LG2, and TIGIT) and high mutation frequency genes (TTN, MET, KMT2C, PKHD1, SETD2, and KMT2D).