Emodin prevents coxsackie virus B3 (CVB3) myocarditis by inhibiting the IL-23/IL-17 inflammatory axis, Th17 cell proliferation, and viral replication in mice, significantly reducing IL-23, IL-17, IL-6, and IL-1β expression levels in the myocardium and serum of CVB3-infected mice (Jiang et al., 2014). This evidence concerns the gene IL17A and myocarditis.