BCL2 and familial pancreatic carcinoma: The results of flow cytometry and Western blot showed that wogonin may enhance the sensitivity of pancreatic cancer cells to gemcitabine by inhibiting p-Akt, anti-apoptotic gene Bcl-2, activating pro-apoptotic gene BAD, and promoting apoptosis of Panc-1 (Figure 4, Figure 5).