GNRH1 and cancer: As shown in Figure 5A, compared with the ND group, the pathways of choline metabolism in cancer, fat digestion and absorption, GnRH signaling pathway, glycerophospholipid metabolism, sphingolipid signaling pathway, cAMP signaling pathway, NF-kB signaling pathway, Th1 and Th2 cell differentiation, T/B cell receptor signaling pathway were destroyed in the model group.