CRP and chronic kidney disease: Moreover, microbial supplements can reduce the level of pro-inflammatory biomarker (CRP), improve the oxidative unbalance among pro-oxidant factors and anti-oxidant enzymes (malondialdehyde, GSH, and TAC), and facilitate the lipid profile (cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol) in CKD patients (30).