The results demonstrated that TMEM59L expression was distinctly negatively correlated with immune infiltration levels in LUSC, SARC, COADREAD, LUAD, HNSC, CESC, BRCA, and TGCT, especially with the levels of CD8 T cell and activated CD4 T cells (Figure 6A and Table S1). Here, TMEM59L is linked to cervical squamous cell carcinoma.