Relative network analysis also indicated that TMEM59L and its interacting genes were involved in cancer-related pathways, such as TSC/mTOR, RTK, EMT, Ras/MAPK, and PI3K/AKT signaling, particularly in ACC, BLCA, COAD, READ, STAD, KIRP, KIRC, KICH, and PAAD (Figure 5C). This evidence concerns the gene AKT1 and cancer.