In mice, both PGD2 and CXCL12 have also been shown to be important in basophil trafficking to secondary lymphoid organs in a murine lupus model, while other studies showed CCL7-dependent migration to the draining lymph nodes in a context of pancreatic tumor or type 2 skin inflammation (91, 93–95). This evidence concerns the gene CXCL12 and systemic lupus erythematosus.