AFP and hepatocellular carcinoma: Our previous study found that broader and stronger SALL4, MAGE-A1, NY-ESO-1, MAGE-A3, and SSX2 (SMNMS)-specific T cell responses correlated with early-stage HCC, while a single T cell response, especially that of α-fetoprotein (AFP)-specific T cells, emerged mainly in the advanced stages (14).