We also verified the protein expression and subcellular localization of IMPDH1 in HCC patients cancer and paired non-cancer tissues by Immunohistochemistry (IHC) (Figure 3C), and supported by IHC results from “The Human Protein Atlas”, which were consistent with the results of bio-informatics analysis (Figure 3D). This evidence concerns the gene IMPDH1 and hepatocellular carcinoma.