Then, we further compared the PTP1B expression in all types of cancers and their adjacent tissues and the result indicated that PTP1B RNA expression was highly expressed in most cancer types except in acute myeloid leukemia (LAML), lung squamous cell carcinoma (LUSC) and uterine corpus endometrial carcinoma (UCEC) (Figure 2C). This evidence concerns the gene PTPN1 and cancer.