In addition, we also investigated the effects of PLK1 mRNA levels on the TIM of GBM by screening seven metagenes, namely, HCK, IgG, Interferon, lymphocyte-specific kinase (LCK), MHC-I, MHC-II, and STAT1, which reflect the status of inflammation and immune responses. This evidence concerns the gene HCK and glioblastoma.