As shown in Figure 5D, in tumor cell-enriched region, the expression of COPS5, DLAT, DLD, FDX1, NFE2L2, PDHA1 and PDHB in the high score group is higher than that in the low score group, while the opposite is true for DLST, GCSH and LIPT2 (P <0.05). Here, NFE2L2 is linked to neoplasm.