showing that IκBNS limits IL6 production in LPS-stimulated macrophages (14), we found higher Il6 levels in wild type compared to IκBNS knock out mice, suggesting that during listeriosis the inflammatory environment and the interplay of different immune cell subsets might influence the regulation of NF-κB-dependent genes by IκBNS. This evidence concerns the gene NFKB1 and listeriosis.