IFNG and neoplasm: Based on the available evidence, combining oncolytic viruses with immune checkpoint blockers creates synergistic responses that can be evaluated and confirmed by increasing the infiltration of antitumor cells in the tumor site and releasing antitumor cytokines such as IFN‐γ.[164] Therefore, increasing the number of oncolytic virus pipelines and the development of immune checkpoint blockers may create a revolution in cancer therapy in the future.