Before PSM, the multivariate regression analysis suggested that albumin levels, maximum tumor size (hazard ratio (HR): 0.978, 95% CI: 0.958–0.999; P=0.042), maximum tumor size (HR: 1.069, 95% CI: 1.028–1.110; P=0.001), TACE session (HR: 0.367, 95% CI: 0.244–0.551; P < 0.001), and alcohol consumption (HR: 1.486, 95% CI: 1.074–2.055; P=0.016) were independent predictors of OS (Table 3). The gene discussed is ALB; the disease is neoplasm.