In order to determine if ferroptosis is affected by PF treatment, we examined the expressions of STAT3/p-STAT3, Nrf2, and GPX4 in PF-treated glioma U87 cells, and found out that all these factors are inhibited at the protein level in a dosage-dependent manner (Figure 6(b)). The gene discussed is NFE2L2; the disease is glioma.