In the group with high NfL, participants with pathologic tau performed worse on Delayed recall (7.1 versus 8.1, p = 0.003, Cohen’s D = 0.64) than the group without normal tau, and the amyloid pathology group also performed worse than the group without amyloid pathology on Delayed recall (7.3 versus 8.1, p = 0.044, Cohen’s D = 0.45). Here, MAPT is linked to amyloidosis.